The 2022 NHL Entry Draft was held on Thursday, July 8, 2022 (1st round) and Friday, July 9, 2022 (2nd to 7th rounds) at the Bell Center in Montreal, Quebec, home of the Montreal Canadiens. The Montreal Canadiens won the draft lottery with the New Jersey Devils winning the second pick and the Arizona Coyotes would draft third. The Canadiens selected Juraj Slafkovsky from HC TPS of the Liiga (Finnish Elite League) with the first overall pick.
The Pittsburgh Penguins would draft 21st overall out of 32 teams in each round after finishing the 2021-22 regular season with 103 points, finishing 12th overall in the National Hockey League standings.
The Pittsburgh Penguins would draft 21st overall out of 32 teams in each round after finishing the 2021-22 regular season with 103 points, finishing 12th overall in the National Hockey League standings.
2022 Pittsburgh Penguins NHL Entry Draft Selections
| Choice | Round | Pick | Overall | Player | Position | 2021-22 Amateur Club |
| 1 | 1 | 21 | 21 | Owen Pickering | D | Swift Current Broncos (WHL) |
| 2 | 4 | 21 | 118 | Sergei Murashov | G | Loko-76 Yaroslavl (Russia-Jr.) |
| 3 | 5 | 21 | 150 | Zam Plante | C | Hermantown (Minnesota) High School Hawks |
| 4 | 6 | 6 | 167 | Nolan Collins | D | Sudbury Wolves (OHL) |
| 5 | 6 | 21 | 182 | Luke Devlin | C | St. Andrew's College Saints (PHC) |
Owen Pickering |
Sergey Murashov |
Zam Plante |
Nolan Collins |
